REASONS OF DONOR DEFERRAL FOR A SINGLE DONOR PLATELETPHERESIS IN A PUBLIC SECTOR BLOOD TRANSFUSION CENTRE OF LAHORE: A CROSS-SECTIONAL STUDY

Tooba Fateen; Sana Haseeb Khan; Saima Farhan; Amna Rani; Rajia Liaqat; Attiq Ur Rehman

doi:10.59058/jaimc.v20i3.40

Authors

Tooba Fateen Allama Iqbal Medical College
Sana Haseeb Khan
Saima Farhan University of Child Health Sciences, The Children Hospital Lahore
Amna Rani Medical Lab technologist, University of Child Health Sciences, The Children Hospital Lahore.
Rajia Liaqat Associate Professor Histopathology, Al-Aleem Medical College Lahore
Attiq Ur Rehman Medical Lab technologist, University of Child Health Sciences, The Children Hospital Lahore.

DOI:

https://doi.org/10.59058/jaimc.v20i3.40

Keywords:

Donor deferral, blood transfusion, donor deferral, plateletpheresis, blood donor, donor exclusion, donor screening

Abstract

Background and Objective: Plateletpheresis is a process by which platelets are extracted from the donor. Donor selection is critical since donors are the sole supply of blood available to satisfy demand. The goal of this study is to investigate the causes behind plateletpheresis donor deferral in order to ensure safe blood donation.

Materials and Methods: The research was carried out at the department of Haematology and Transfusion Medicine University of Child Health Sciences, The Children Hospital Lahore. 50 plateletpheresis donors who voluntarily came for donation were considered for the procedure as per guidelines and departmental standard operating procedure. The details of the procedure of plateletpheresis were explained to each donor. Donor questionnaire was filled including brief history, general physical examination, Haematological parameters such as haemoglobin and the donor blood screening was done to be considered fit for procedure. The reasons for deferral of donors were noted after all work up was done. Informed consent was taken before the procedure. Plateletpheresis was done using COM.TEC Cell Separator instrument.

Results: In this study 50 donors were included. Out of 50 donors 34 were approved for procedure and 16 were deferred due to different temporary and permanent reasons. The age of the donors were in between 18 to 50 years. Major reason for temporary deferral was poor venous access (n=7, 14%) followed by the low haemoglobin value (n=4, 8%). Other reasons for temporary deferral were history of medication (n=3, 6%), low platelet count (n=4,8%), history of blood transfusion (n=1, 2%), history of vaccination n=2, 4%), leucocytosis (n=1, 2%), underweight (n=4, 8%), fever (n=1, 2%), refusal after questionnaire (n=1, 2%), seropositive for malaria and VDRL (n=3, 6%), high blood pressure (n=1, 2%), and anxiety (n=1, 2%). Permanent reasons for deferral were seropositive for HbsAg (n=2, 4%), seropositive for HCV (n=4, 8%) and tattoo (n=1, 2%).

Conclusion: This study found a pattern of donor deferral in single donor platelet apheresis that was our experience in single centre. In conclusion during the selection of donors, Transfusion services should be very careful related to donor safety measures and these causes of deferral should be kept in mind.

Author Biographies

Saima Farhan, University of Child Health Sciences, The Children Hospital Lahore

Associate Professor Pediatric Hematology

Rajia Liaqat, Associate Professor Histopathology, Al-Aleem Medical College Lahore

Associate Professor histopathology

Attiq Ur Rehman, Medical Lab technologist, University of Child Health Sciences, The Children Hospital Lahore.

Medical Lab Technologist

References

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