METABOLIC SYNDROME IN PATIENTS OF CHRONIC KIDNEY DISEASE PRESENTING TO THE NEPHROLOGY DEPARTMENT OF A TERTIARY CARE HOSPITAL
DOI:
https://doi.org/10.59058/jaimc.v21i1.102Keywords:
chronic kidney disease (CKD), metabolic syndrome (MetS), end-stage renal disease (ESRD)Abstract
BACKGROUND AND OBJECTIVE: The prevalence of metabolic syndrome (MetS) is on rise and is proven to be a known factor for cardiovascular diseases. However, its association with chronic kidney disease is also emerging which can accentuate the risk of cardiovascular events in patients of CKD. Therefore, this study was conducted to determine the frequency of metabolic syndrome and its related factors among patients with chronic kidney disease presenting to the Nephrology outdoor.
MATERIAL AND METHODS: it was a cross sectional study conducted at Nephrology department Jinnah hospital Lahore. About 110 patients of CKD diagnosed for atleast 6 months, aged 18-60 and fulfilling the selection criteria were enrolled after an informed consent by non-probability consecutive sampling. Measurement of blood pressure and central obesity was done as per standard protocol and all the information was recorded in proforma. A 5 ml of blood sample was taken for triglyceride, HDL, and fasting blood sugar levels after ensuring overnight fasting. Frequency percentages were calculated for qualitative variables by using SPSS26. Chi-square test was applied to check statistical significance between metabolic syndrome and effect modifiers.
RESULTS: The Mean age of patients was 42.46 + 5.580 with about 63(57%) being male. Majority had CKD stage-V 64(58%), and had the disease for more than 5 years i.e. 75(68%). The frequency of MetS was 39(35%) with that of high blood pressure 68(62%) being the most common among all components, followed by high fasting plasma glucose levels 52(47%), high triglyceride levels 35(32%), high HDL levels 32(29%) and central obesity 30(27%). A statistically insignificant relationship of MetS was seen on stratification for age, gender, duration, and stage of CKD.
CONCLUSION: It can be concluded that a considerable frequency of MetS 35% is present among patients with CKD. Thus, there is a dire need to screen all the patients with CKD for the presence of MetS as an essential component of their routine follow up. This will help in its early diagnosis and management which may halt the disease progression and decrease the morbidity and mortality associated with this lethal but manageable double burden of disease.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Muhammad Asad Saeed, Mehwish Akhtar, Muhammad Abdullah Munir, Kashif Ayub, Tamoor Nazir, Maria Arshad, Hira Samad
This work is licensed under a Creative Commons Attribution 4.0 International License.
The articles published in this journal come under creative commons licence Attribution 4.0 International (CC BY 4.0) which allows to copy and redistribute the material in any medium or format Adapt — remix, transform, and build upon the material for any purpose, even commercially under following terms.
-
Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
The editorial board of the Journal strives hard for the authenticity and accuracy of the material published in the Journal. However, findings and statements are views of the authors and do not necessarily represent views of the Editorial Board. Many software like (Google Maps, Google Earth, Biorender (free version)) restricts the free distribution of materials prepared using these softwares. Therefore, authors are strongly advised to check the license/copyright information of the software used to prepare maps/images. In case of publication of copyright material, the correction will be published in one of the subsequent issues of the Journal, and the authors will bear the printing cost.
