A 42-Year-old Man with Acromegaly and Related Complications: A Case Report Highlighting the Importance of Early Diagnosis of a Rare Condition and its Further Management
DOI:
https://doi.org/10.59058/jaimc.v21i3.182Keywords:
acromegalyAbstract
Acromegaly is a rare and underdiagnosed disorder
which is caused by a growth hormone (GH)-
1
secreting pituitary adenoma . Acromegaly has a prevalence of 60 cases permillion and an incidence of 3-4
per million per year. The average age at presentation
is about 44 years and both genders appearto be equally
2
affected . Persistent excess of both growth hormone
and its target hormone insulin-like growth factor 1
(IGF-1)inAcromegaly resultsin awide array of cardiovascular, respiratory, metabolic, musculoskeletal,
neurological, and neoplastic comorbidities that might
3
not be reversible with disease control. Acromegaly
is diagnosed with elevated serum insulin-like growth
factor-1 and lack of growth hormone suppression after
glucose administration4. Normalization of IGF-1 and
growth hormone are the primary therapeutic aims;
additional treatment goals include tumor shrinkage,
managing complications, reducing excess morbidity,
and improving quality of life.
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Copyright (c) 2023 Bilal Yasir Khan, Alisaa K C Tariq, Sumana Kundu, Hazrat Ullah, Lubna Mirza
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